Laboratory of Organic Synthesis

PI: doc. RNDr. Ctibor Mazal, CSc.

 

We are involved in synthesis of molecular building blocks, the macrocyclic in particular, and in investigation of their molecular and supramolecular properties with respect to possible applications in other fields of chemistry and materials sciences.

Research Topics

• Shape persistent fully conjugated and non-conjugated macrocycles
• Bicyclo[1.1]pentane chemistry

Selected Publications

   Phulwale B. V., Mishra S. K., Nečas M., Mazal C. Phenanthrylene-Butadiynylene and Phenanthrylene-Thienylene Macrocycles: Synthesis, Structure, and Properties. Org. Chem. 2016, 81, 6244-6252.
   Kaleta J., Janoušek .Z, Nečas M., Mazal C. Molecular Rods Combining o-Carborane and Bicyclo[1.1.1]pentane Cages: An Insertion of the Triple Bond Located Next to a Highly Strained Cage. Organometallics 2015, 34, 967-972.
   Kaleta J., Nečas M., Mazal C. 1,3-Diethynylbicyclo[1.1.1]pentane, A Useful Molecular Building Block. J. Org. Chem. 2012, 4783-4796.
   Kaleta J., Mazal C. A Triangular Macrocycle Altering Planar and Bulky Sections in its Molecular Backbone Org. Lett. 2011, 13, 1326-1329.

 

         

  

laboratory of organic photochemistry laboratory of organic synthesis laboratory of organic synthesis and medicinal chemistry supramolecular chemistry group