Laboratory of Organic Photochemistry

PI: prof. RNDr. Petr Klán, Ph.D.
URL: http://photochem.sci.muni.cz

 

The laboratory is engaged in a variety of research projects that are dealing with development of photoactivatable compounds, fluorescent tags and molecular sensors for biology, mechanisms of photochemical transformations, and environmental photochemistry. The research group is equipped with femtosecond and nanosecond flash photolysis instrumentation, absorption and fluorescence spectrometers, and photoreactors.

Multidisciplinary work in this laboratory involves organic synthesis, molecular spectroscopy, chemical kinetics, structure determination of organic molecules, time-resolved spectroscopic methods, and computational chemistry. Students have the opportunity to work on projects in collaboration with leading foreign and domestic scientific groups and present their results at international conferences.

Research Topics

• Photoactivatable compounds
• Fluorophores
• Molecular sensors
• Kinetic flash photolysis and spectroscopy
• Organic synthesis using photochemical steps
• Photochemistry and photophysics of organic compounds in cryosphere

Selected Publications

   Šolomek T., Wirz J., Klán P. Searching for Improved Photoreleasing Abilities of Organic Molecules. Acc. Chem. Res. 2015, 48, 3064.
   Palao E., Slanina T., Muchová L., Šolomek T., Vítek L., Klán P. Transition-Metal-Free CO-Releasing BODIPY Derivatives Activatable by Visible to NIR Light as Promising Bioactive Molecules. J. Am. Chem. Soc. 2016, 138, 126.
   Ludvíková L., Friš P., Heger D., Wirz J., Šebej P., Klán P. Photochemistry of Rose Bengal in Water and Acetonitrile: A Comprehensive Kinetic Analysis. Phys. Chem. Chem. Phys. 2016, 18, 16266.
   Horváth P., Šebej P., Šolomek T., Klán P. Small-Molecule Fluorophores with Large Stokes Shifts: 9-Iminopyronin Analogues as Clickable Tags. J. Org. Chem. 2015, 80, 1299.
   Šolomek T., Heger D., Ngoy B. P., Givens R. S., Klán P. The Pivotal Role of Oxyallyl Diradicals in Photo-Favorskii Rearrangements: Transient Spectroscopic and Computational Studies. J. Am. Chem. Soc. 2013, 135, 15209.
   Ray D., K'Ekuboni Malongwe J., Klán P. Rate Acceleration of the Heterogeneous Reaction of Ozone with a Model Alkene at the Air-Ice Interface at Low Temperatures. Environ. Sci. Technol. 2013, 47, 6773.

 

  

laboratory of organic photochemistry laboratory of organic synthesis laboratory of organic synthesis and medicinal chemistry supramolecular chemistry group